Лікарі повинні підтримувати еутиреоз у пацієнтів під час лікування гормо...

Comments

Post a Comment

Popular posts from this blog

Beyond the Dichotomy: When a Heart Attack and Broken Heart Syndrome Are One

Image
  Science rarely arrives as a single revelation. More often, it accumulates — in clinical observations that don't fit the textbook, in questions that outlast careers, and in the partnerships that make sustained thinking possible. The theory I want to describe here is the product of all three. Vladimir Shlyakhover was once my student. He has long since become my colleague in science and my friend in life. We are both from Ukraine — he now lives in Israel, I in the United States. Between us we carry decades of clinical and research experience with the heart under stress. And together we have arrived at something we no longer call a hypothesis. We call it a theory — because the evidence, in our view, demands that elevation. The Two Diagnoses That Should Not Be Separate Cardiology has long maintained a clean boundary between two cardiac conditions. Acute myocardial infarction (AMI)  — the classic heart attack — is understood as the consequence of a blocked coronary artery: oxygen ...
Read more

Beyond Inflammation: Chronic Rheumatic Pain as a Stable Pathological Functional System

Image
The contemporary discussion of chronic rheumatic pain has begun to move beyond a narrow inflammatory model. Recent reporting from EULAR 2026 emphasized that a substantial proportion of patients continue to experience severe or unacceptable pain years after diagnosis, even in the context of anti-inflammatory treatment, and proposed several important contributors to this persistent burden, including nociplastic pain, poor sleep, psychological distress, and kinesiophobia. This shift is important because it recognizes that pain persistence cannot always be explained by active inflammation alone.  Yet the findings may support an even deeper interpretation. Rather than viewing these variables as separate complicating factors layered onto inflammatory disease, it may be more accurate to understand them as elements of a unified pathological organization. In this view, chronic rheumatic pain can evolve into a relatively stable pathological functional system, one in which altered nociceptive...
Read more

The Universe Optimizes — and So Does the Human Body

   Nature does not waste. Light bends through a prism along the fastest possible path. Planets trace ellipses rather than spirals because ellipses cost less energy to maintain. Mechanical systems, from pendulums to galaxies, follow paths of least action. This is not coincidence or aesthetic preference — it is the deepest operating principle of the physical universe. And remarkably, the same logic runs through every cell, organ, and lifetime of a human being. The principle of optimality states that any system navigating from one state to another will, given sufficient time and freedom, converge on the most efficient path available. In mathematics, this is formalized precisely: among all possible trajectories a controllable system might follow, certain ones are superior — minimizing cost, time, or resource expenditure. What makes this principle arresting is not its mathematical elegance but its universality. It does not stop at physics. It continues, unbroken, into biology. The...
Read more